Darwin-L Message Log 8:101 (April 1994)

Academic Discussion on the History and Theory of the Historical Sciences

This is one message from the Archives of Darwin-L (1993–1997), a professional discussion group on the history and theory of the historical sciences.

Note: Additional publications on evolution and the historical sciences by the Darwin-L list owner are available on SSRN.

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<8:101>From @SIVM.SI.EDU:IRMSS668@SIVM.SI.EDU  Wed Apr 27 13:56:58 1994

Date: Wed, 27 Apr 1994 13:21:43 -0400 (EDT)
From: Jim Felley <IRMSS668@sivm.si.edu>
Subject: Vitamin C
To: darwin-l@ukanaix.cc.ukans.edu

Paul DeBenedictis wrote
"...Note that this explanation requires no selection. It's just something that
happens, but it happens because there is no selection on the loci in question."

Paul is right on target.  This effect is known as "Muller's ratchet" ...
multiple mutations on a locus free of selection tend to progressively destroy
the function of its product.  Leslie and Vrijenhoek, Evolution
1988(??) demonstrated the effect.
                   Jim

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